3,4,5-Tricaffeoylquinic acid
| Code | Size | Price |
|---|
| TAR-TN1235-5mg | 5mg | £2,085.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α?- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like receptor 4 expression-mediated activation of the Akt, ERK and NF-κB pathways, it may exert an inhibitory effect against the pro-inflammatory mediator-induced skin disease.
CAS:
86632-03-3
Formula:
C34H30O15
Molecular Weight:
678.599
Pathway:
Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Microbiology/Virology; Apoptosis
Purity:
0.98
SMILES:
OC(=O)[C@@]1(O)C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H](C1)OC(=O)C=Cc1ccc(O)c(O)c1
Target:
TNF; Akt; HIV Protease
References
3,4,5-Tricaffeoylquinic acid inhibits tumor necrosis factor-??-stimulated production of inflammatory mediators in keratinocytes via suppression of Akt- and NF-?B-pathways.Int Immunopharmacol. 2011 Nov;11(11):1715-23.