TargetMol

Hellebrigenin

Product Code:
 
TAR-TN1728
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1728-5mg5mg£792.00
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Further Information

Bioactivity:
Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Hellebrigenin exhibites moderate to strong activity against human HL-60, SF-295, MDA-MB-435, and HCT-8 cancer cell strains without hemolysis of mouse erythrocytes.
CAS:
465-90-7
Formula:
C24H32O6
Molecular Weight:
416.514
Pathway:
PI3K/Akt/mTOR signaling; Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.98
SMILES:
[H][C@@]12CC[C@]3(O)C[C@@H](O)CC[C@]3(C=O)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@]21O)c1ccc(=O)oc1
Target:
PARP; Akt; CDK

References

Cytotoxic profile of natural and some modified bufadienolides from toad Rhinella schneideri parotoid gland secretionToxicon, 2010, 56(3):339-348.