Sanggenol L
| Code | Size | Price |
|---|
| TAR-TN2177-5mg | 5mg | £336.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN2177-1mL | 1 mL * 10 mM (in DMSO) | £352.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apoptosis via caspase activation and inhibition of NF-κB/IκBα? phosphorylation as a potent chemotherapeutic agent for ovarian cancers.
CAS:
329319-20-2
Formula:
C25H26O6
Molecular Weight:
422.477
Pathway:
NF-κb; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
CC(C)=CCCC1(C)Oc2cc(O)c3C(=O)CC(Oc3c2C=C1)c1ccc(O)cc1O
Target:
c-Myc; NF-κB
References
Isoprenylated flavonoids from the root bark of Morus alba and their hepatoprotective and neuroprotective activities.Arch Pharm Res. 2015 Nov;38(11):2066-75.