MK-0812
Code | Size | Price |
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TAR-TQ0182-5mg | 5mg | £1,332.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0182-50mg | 50mg | £2,625.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0182-100mg | 100mg | £3,524.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
MK-0812 is an effective and specific CCR2 antagonist.
CAS:
624733-88-6
Formula:
C24H34F3N3O3
Molecular Weight:
469.549
Pathway:
Immunology/Inflammation; Microbiology/Virology
Purity:
0.98
SMILES:
COC1COCCC1NC1CCC(C1)(C(C)C)C(=O)N1CCc2ncc(cc2C1)C(F)(F)F
Target:
CCR
References
Sugiyama S, Yumimoto K, Fujinuma S, et al.Identification of effective CCR2 inhibitors for cancer therapy using humanized mice.The Journal of Biochemistry.2023: mvad086.
Wisniewski T, et al. Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist.J Immunol Methods. 2010 Jan 31;352(1-2):101-10.
Min SH, et al. Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis.Biochem Biophys Res Commun. 2010 Jan 1;391(1):1080-6.