Carbamazepine
Code | Size | Price |
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TAR-T0943-100mg | 100mg | £100.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0943-1mL | 1 mL * 10 mM (in DMSO) | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0943-200mg | 200mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0943-500mg | 500mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Carbamazepine is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity is not understood; however, carbamazepine is commonly used to treat pain associated with trigeminal neuralgia.
CAS:
298-46-4
Formula:
C15H12N2O
Molecular Weight:
236.274
Pathway:
Membrane transporter/Ion channel; Autophagy
Purity:
0.9988
SMILES:
NC(=O)N1c2ccccc2C=Cc2ccccc12
Target:
Mitophagy; Sodium Channel; Autophagy
References
1. Willow M, et al. Mol Pharmacol, 1982, 22(3), 627-635.
2. Okada M, et al. Epilepsy Res, 1997, 28(2), 143-153.
3. Serra M, et al. Neuropharmacology, 2000, 39(12), 2448-2456.
4. Li H, Zhou D S, Chang H, et al. Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder[J]. Journal of psychiatric research. 2019.
5. . Carbamazepine promotes specific stimuli induced NLRP3 inflammasome activation and causes idiosyncratic liver injury in mice . Archives of Toxicology. 2019