bio-THZ1
Code | Size | Price |
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TAR-T10546-10mg | 10mg | £1,916.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T10546-25mg | 25mg | £3,854.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
bio-THZ1 is a biotinylated version of THZ1. THZ1 is a selective and irreversibly covalent CDK7 inhibitor (IC50: 3.2 nM).
CAS:
1604811-14-4
Formula:
C52H65ClN12O8S
Molecular Weight:
1053.68
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
[H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCNC(=O)NCCCN(C)CC=CC(=O)Nc3ccc(cc3)C(=O)Nc3cccc(Nc4ncc(Cl)c(n4)-c4c[nH]c5ccccc45)c3)[C@@]1([H])NC(=O)N2
Target:
CDK
References
1. Kwiatkowski N, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014 Jul 31;511(7511):616-20.