Corin

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TargetMol
Product Code: TAR-T10864
Supplier: TargetMol
CodeSizePrice
TAR-T10864-1mg1mg£214.00
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TAR-T10864-5mg5mg£436.00
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TAR-T10864-1mL1 mL * 10 mM (in DMSO)£464.00
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TAR-T10864-10mg10mg£610.00
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TAR-T10864-25mg25mg£922.00
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TAR-T10864-50mg50mg£1,219.00
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TAR-T10864-100mg100mg£1,613.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Corin is a dual inhibitor of histone lysine-specific demethylase (LSD1) and HDAC (Ki(inact): 110 nM for LSD1; IC50: 147 nM for HDAC1).
CAS:
1808113-09-8
Formula:
C26H28N4O2
Molecular Weight:
428.536
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
N[C@@H]1C[C@H]1c1ccc(NC(=O)CCCc2ccc(cc2)C(=O)Nc2ccccc2N)cc1
Target:
Histone Demethylase

References

1. Kalin JH, et al. Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nat Commun. 2018 Jan 4;9(1):53.