Cytochalasin A
| Code | Size | Price |
|---|
| TAR-T10928-10mg | 10mg | £630.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and bactericidal active agent.
CAS:
14110-64-6
Formula:
C29H35NO5
Molecular Weight:
477.601
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.98
SMILES:
[H][C@]12[C@H](Cc3ccccc3)NC(=O)[C@]11OC(=O)C=CC(=O)CCC[C@@H](C)CC=C[C@@]1([H])[C@H](O)C(=C)[C@H]2C
Target:
HIV Protease
References
1. Kerman K, et al. An electrochemical approach for the detection of HIV-1 protease. Chem Commun (Camb). 2007 Oct 7;(37):3829-31.
2. Antonio Bottalico, et al. Cytochalasins: Structure-activity relationships. Phytochemistry Volume 29, Issue 1, 1990.