TargetMol

eIF4A3-IN-2

Product Code:
 
TAR-T11171
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11171-5mg5mg£437.00
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Quantity:
TAR-T11171-50mg50mg£1,830.00
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Quantity:
TAR-T11171-100mg100mg£2,697.00
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This product comes from: United States.
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Further Information

Bioactivity:
eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.
CAS:
2095677-20-4
Formula:
C25H19Br2ClN4O2
Molecular Weight:
602.71
Purity:
0.98
SMILES:
Clc1ccc(cc1)[C@H]1CN(CCN1C(=O)c1ccc(Br)cc1)C(=O)c1cnn2cc(Br)ccc12

References

1. Iwatani-Yoshihara M, et al. Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay. ACS Chem Biol. 2017 Jul 21;12(7):1760-1768.