Mitotane
Code | Size | Price |
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TAR-T1199-50mg | 50mg | £95.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1199-100mg | 100mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1199-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1199-200mg | 200mg | £117.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1199-500mg | 500mg | £142.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Mitotane is a derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
CAS:
53-19-0
Formula:
C14H10Cl4
Molecular Weight:
320.03
Pathway:
Apoptosis; Neuroscience
Purity:
0.9975
SMILES:
ClC(Cl)C(c1ccc(Cl)cc1)c1ccccc1Cl
Target:
Apoptosis; AChR
References
1. Zatelli MC, et al. Endocrinology,2010, 151(6), 2453-2561.
2. Lin CW, et al. Toxicology,2012, 298(1-3), 14-23.
3. Germano A, et al. Mol Cell Endocrinol. 2014 Jan 25;382(1):1-7.
4. Martz F, et al. Res Commun Chem Pathol Pharmacol,1976, 13(1), 83-92.