NXT629
Code | Size | Price |
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TAR-T12278-5mg | 5mg | £502.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T12278-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T12278-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
NXT629 is a selective and competitive antagonist of PPAR-α(human PPARα with an IC50 of 77 nM).
CAS:
1454925-59-7
Formula:
C35H39N5O3S
Molecular Weight:
609.79
Pathway:
Endocrinology/Hormones
Purity:
0.98
SMILES:
CCn1c(CCCc2ccc(cc2)-c2ccc(NS(=O)(=O)c3ccccc3)cn2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O
Target:
Estrogen/progestogen Receptor
References
1. Bravo Y, et al. Identification of the first potent, selective and bioavailable PPAR? antagonist. Bioorg Med Chem Lett. 2014 May 15;24(10):2267-72.
2. Stebbins KJ, et al. In vitro and in vivo pharmacology of NXT629, a novel and selective PPAR? antagonist. Eur J Pharmacol. 2017 Aug 15;809:130-140.