Plecanatide acetate
Code | Size | Price |
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TAR-T12501-10mg | 10mg | £630.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.
CAS:
1075732-84-1
Formula:
C67H108N18O28S4
Molecular Weight:
1741.94
Purity:
0.98
SMILES:
OC(C)=O.[NDECELCVNV ACTGCL]
References
1. Shailubhai K, et al. Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis. World J Gastrointest Pharmacol Ther. 2015 Nov 6;6(4):213-22.