TargetMol

Pelitrexol

Product Code:
 
TAR-T14147
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14147-5mg5mg£457.00
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Quantity:
TAR-T14147-50mg50mg£1,669.00
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Quantity:
TAR-T14147-100mg100mg£2,729.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Pelitrexol (AG 2037) is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor.
CAS:
446022-33-9
Formula:
C20H25N5O6S
Molecular Weight:
463.51
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Purity:
0.98
SMILES:
Cc1cc(sc1CC[C@@H]1CNc2nc(N)[nH]c(=O)c2C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Target:
DHFR

References

1. Emmanuel N, et al. Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase. Cell Rep. 2017 Jun 27;19(13):2665-2680.