Pelitrexol

TargetMol
Product Code: TAR-T14147
Supplier: TargetMol
CodeSizePrice
TAR-T14147-5mg5mg£457.00
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Quantity:
TAR-T14147-50mg50mg£1,669.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T14147-100mg100mg£2,729.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Pelitrexol (AG 2037) is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor.
CAS:
446022-33-9
Formula:
C20H25N5O6S
Molecular Weight:
463.51
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Purity:
0.98
SMILES:
Cc1cc(sc1CC[C@@H]1CNc2nc(N)[nH]c(=O)c2C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Target:
DHFR

References

1. Emmanuel N, et al. Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase. Cell Rep. 2017 Jun 27;19(13):2665-2680.