TargetMol

p-MPPI hydrochloride

Product Code:
 
TAR-T16421
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16421-10mg10mg£139.00
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TAR-T16421-1mL1 mL * 10 mM (in DMSO)£144.00
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TAR-T16421-25mg25mg£189.00
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TAR-T16421-50mg50mg£269.00
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TAR-T16421-100mg100mg£385.00
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This product comes from: United States.
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Further Information

Bioactivity:
p-MPPI hydrochloride is a selective antagonist of 5-HT1A receptor, and has antidepressant and anxiolytic-like effects.
CAS:
220643-77-6
Formula:
C25H28ClIN4O2
Molecular Weight:
578.88
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9925
SMILES:
Cl.COc1ccccc1N1CCN(CCN(C(=O)c2ccc(I)cc2)c2ccccn2)CC1
Target:
5-HT Receptor

References

1. S?rensen E, et al. The selective 5-HT(1A) receptor antagonist p-MPPI antagonizes sleep--waking and behavioural effects of 8-OH-DPAT in rats. Behav Brain Res. 2001 Jun;121(1-2):181-7. 2. Cao BJ, et al. Anxiolytic-like profile of p-MPPI, a novel 5HT1A receptor antagonist, in the murine elevated plus-maze. Psychopharmacology (Berl). 1997 Feb;129(4):365-71.