TargetMol

NCX 1000

Product Code:
 
TAR-T19471
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T19471-5mg5mg£508.00
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Quantity:
TAR-T19471-50mg50mg£1,661.00
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Quantity:
TAR-T19471-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NCX 1000 is a liver-specific NO donor compound,NCX 1000 derived from ursodeoxycholic acid (UDCA).
CAS:
401519-96-8
Formula:
C38H55NO10
Molecular Weight:
685.855
Purity:
0.98
SMILES:
COc1cc(C=CC(=O)OCCCCO[N+]([O-])=O)ccc1OC(=O)CCC(C)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C

References

1. Fiorucci S, et al. NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8897-902. Epub 2001 Jul 10. 2. Fiorucci S, et al. NCX-1000, a nitric oxide-releasing derivative of ursodeoxycholic acid, ameliorates portal hypertension and lowers norepinephrine-induced intrahepatic resistance in the isolated and perfused rat liver. J Hepatol. 2003 Dec;39(6):932-9.