Cyclo-L-Trp-L-Trp
| Code | Size | Price |
|---|
| TAR-T19717-25mg | 25mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cyclo-L-Trp-L-Trp is a broad-spectrum antifungal. It also induces a high degree of acetylation of histones.
CAS:
20829-55-4
Formula:
C22H20N4O2
Molecular Weight:
372.428
Pathway:
Microbiology/Virology
Purity:
0.9637
SMILES:
O=C1N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H]1Cc1c[nH]c2ccccc12
Target:
Antifungal
References
1. Lu C, Xie F, Shan C, Shen Y. Two novel cyclic hexapeptides from the genetically engineered Actinosynnema pretiosum. Appl Microbiol Biotechnol. 2017 Mar;101(6):2273-2279. doi: 10.1007/s00253-016-8017-3. Epub 2016 Dec 2. PubMed PMID: 27913850.
2. James ED, Knuckley B, Alqahtani N, Porwal S, Ban J, Karty JA, Viswanathan R, Lane AL. Two Distinct Cyclodipeptide Synthases from a Marine Actinomycete Catalyze Biosynthesis of the Same Diketopiperazine Natural Product. ACS Synth Biol. 2016 Jul 15;5(7):547-53. doi: 10.1021/acssynbio.5b00120. Epub 2015 Dec 9. PubMed PMID: 26641496.
3. Alqahtani N, Porwal SK, James ED, Bis DM, Karty JA, Lane AL, Viswanathan R. Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis. Org Biomol Chem. 2015 Jul 14;13(26):7177-92. doi: 10.1039/c5ob00537j. Epub 2015 May 29. Erratum in: Org Biomol Chem. 2015 Sep 21;13(35):9323. PubMed PMID: 26022437.
4. Li XB, Li YL, Zhou JC, Yuan HQ, Wang XN, Lou HX. A new diketopiperazine heterodimer from an endophytic fungus Aspergillus niger. J Asian Nat Prod Res. 2015;17(2):182-7. doi: 10.1080/10286020.2014.959939. Epub 2014 Nov 17. PubMed PMID: 25401948.