CCG-1423

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TargetMol
Product Code: TAR-T2014
Supplier: TargetMol
CodeSizePrice
TAR-T2014-5mg5mg£96.00
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Quantity:
TAR-T2014-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T2014-10mg10mg£112.00
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Quantity:
TAR-T2014-25mg25mg£148.00
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Quantity:
TAR-T2014-50mg50mg£203.00
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Quantity:
TAR-T2014-100mg100mg£291.00
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Quantity:
TAR-T2014-200mg200mg£414.00
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TAR-T2014-500mg500mg£629.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.
CAS:
285986-88-1
Formula:
C18H13ClF6N2O3
Molecular Weight:
454.75
Pathway:
GPCR/G Protein; Autophagy; Cell Cycle/Checkpoint; MAPK
Purity:
0.9998
SMILES:
CC(ONC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)Nc1ccc(Cl)cc1
Target:
LRRK2; Rho; Ras

References

1. Evelyn CR, et al. Mol Cancer Ther. 2007, 6(8), 2249-2260. 2. Mae S, et al. Biochem Biophys Res Commun. 2010, 393(4), 877-882. 3. Chong NW, et al. PLoS One. 2012, 7(7), e40966. 4. Johnson LA, et al. Inflamm Bowel Dis. 2014, 20(1), 154-165.