Motesanib Diphosphate

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TargetMol
Product Code: TAR-T2288L
Supplier: TargetMol
CodeSizePrice
TAR-T2288L-5mg5mg£99.00
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TAR-T2288L-10mg10mg£112.00
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TAR-T2288L-1mL1 mL * 10 mM (in DMSO)£114.00
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Quantity:
TAR-T2288L-25mg25mg£148.00
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Quantity:
TAR-T2288L-50mg50mg£208.00
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TAR-T2288L-100mg100mg£309.00
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Quantity:
TAR-T2288L-500mg500mg£655.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Motesanib Diphosphate is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity.
CAS:
857876-30-3
Formula:
C22H29N5O9P2
Molecular Weight:
569.448
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
OP(O)(O)=O.OP(O)(O)=O.CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12
Target:
VEGFR; c-Kit

References

1. Polverino A, et al. Cancer Res, 2006, 66(17), 8715-8721. 2. Kruser TJ, et al. Clin Cancer Res, 2010, 16(14), 3639-3647. 3. Coxon A, et al. Clin Cancer Res, 2009, 15(1), 110-118.