alpha-Conotoxin imi
| Code | Size | Price |
|---|
| TAR-T23707-10mg | 10mg | £1,061.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.
CAS:
156467-85-5
Formula:
C52H82N20O15S4
Molecular Weight:
1355.59
Purity:
0.98
SMILES:
C[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)CN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(N)=O
References
1. Mei D, Zhao L, Chen B, Zhang X, Wang X, Yu Z, Ni X, Zhang Q. ?-Conotoxin ImI-modified polymeric micelles as potential nanocarriers for targeted docetaxel delivery to ?7-nAChR overexpressed non-small cell lung cancer. Drug Deliv. 2018 Nov;25(1):493-503. doi: 10.1080/10717544.2018.1436097. PubMed PMID: 29426250.
2. Padilla A, Keating P, Hartmann JX, Mar? F. Effects of ?-conotoxin ImI on TNF-?, IL-8 and TGF-? expression by human macrophage-like cells derived from THP-1 pre-monocytic leukemic cells. Sci Rep. 2017 Oct 6;7(1):12742. doi: 10.1038/s41598-017-11586-2. PubMed PMID: 28986583; PubMed Central PMCID: PMC5630575.
3. Gao B, Peng C, Lin B, Chen Q, Zhang J, Shi Q. Screening and Validation of Highly-Efficient Insecticidal Conotoxins from a Transcriptome-Based Dataset of Chinese Tubular Cone Snail. Toxins (Basel). 2017 Jul 6;9(7). pii: E214. doi: 10.3390/toxins9070214. PubMed PMID: 28684723; PubMed Central PMCID: PMC5535161.
4. Taguchi A, Kobayashi K, Kotani A, Muguruma K, Kobayashi M, Fukumoto K, Takayama K, Hakamata H, Hayashi Y. 3-Nitro-2-pyridinesulfenates as Efficient Solution- and Solid-Phase Disulfide Bond Forming Agents. Chemistry. 2017 Jun 16;23(34):8262-8267. doi: 10.1002/chem.201700952. Epub 2017 May 29. PubMed PMID: 28407456.