TargetMol

Hh-Ag1.5

Product Code:
 
TAR-T24754
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24754-5mg5mg£390.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24754-50mg50mg£1,797.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24754-100mg100mg£2,560.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SAG1.5 is an agonist of the smoothened receptor.
CAS:
612542-14-0
Formula:
C28H26ClF2N3OS
Molecular Weight:
526.04
Pathway:
GPCR/G Protein|Stem Cells
Purity:
0.98
SMILES:
CN[C@H]1CC[C@@H](CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2c(F)ccc(F)c2c1Cl
Target:
Hedgehog/Smoothened

References

1. Wang C, Wu H, Evron T, Vardy E, Han GW, Huang XP, Hufeisen SJ, Mangano TJ, Urban DJ, Katritch V, Cherezov V, Caron MG, Roth BL, Stevens RC. Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nat Commun. 2014 Jul 10;5:4355. doi: 10.1038/ncomms5355. PubMed PMID: 25008467; PubMed Central PMCID: PMC4198951.