3 α,21-Dihydroxy-5 α-pregnan-20-one
| Code | Size | Price |
|---|
| TAR-T26390-5mg | 5mg | £244.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26390-50mg | 50mg | £962.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26390-100mg | 100mg | £1,508.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
5alpha-THDOC is a positive allosteric GABAA receptors modulator.
CAS:
567-02-2
Formula:
C21H34O3
Molecular Weight:
334.5
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](C(=O)CO)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@H](O)CC[C@]12C
References
1. Ghosh B, Tsao TW, Czajkowski C. A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation. Neuropharmacology. 2017 Oct;125:343-352. doi: 10.1016/j.neuropharm.2017.08.007. Epub 2017 Aug 10. PubMed PMID: 28803966; PubMed Central PMCID: PMC5600277.
2. Jensen JP, Nipper MA, Helms ML, Ford MM, Crabbe JC, Rossi DJ, Finn DA. Ethanol withdrawal-induced dysregulation of neurosteroid levels in plasma, cortex, and hippocampus in genetic animal models of high and low withdrawal. Psychopharmacology (Berl). 2017 Sep;234(18):2793-2811. doi: 10.1007/s00213-017-4671-0. Epub 2017 Jun 29. PubMed PMID: 28664280.
3. Krohmer A, Brehm M, Auw?rter V, Szabo B. Pregnenolone does not interfere with the effects of cannabinoids on synaptic transmission in the cerebellum and the nucleus accumbens. Pharmacol Res. 2017 Sep;123:51-61. doi: 10.1016/j.phrs.2017.04.032. Epub 2017 Jun 24. PubMed PMID: 28655644.
4. Park MH, Rehman SU, Kim IS, Choi MS, Yoo HH. Stress-induced changes of neurosteroid profiles in rat brain and plasma under immobilized condition. J Pharm Biomed Anal. 2017 May 10;138:92-99. doi: 10.1016/j.jpba.2017.02.007. Epub 2017 Feb 3. PubMed PMID: 28189891.