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TargetMol
Product Code: TAR-T32088
Supplier: TargetMol
CodeSizePrice
TAR-T32088-1mg1mg£249.00
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TAR-T32088-5mg5mg£523.00
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Quantity:
TAR-T32088-1mL1 mL * 10 mM (in DMSO)£567.00
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Quantity:
TAR-T32088-10mg10mg£706.00
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Quantity:
TAR-T32088-25mg25mg£1,058.00
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Quantity:
TAR-T32088-50mg50mg£1,412.00
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Quantity:
TAR-T32088-100mg100mg£1,878.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
HMPL-523 is an oral spleen tyrosine kinase (Syk) inhibitor that binds to and inhibits the activity of Syk, thereby inhibiting B cell receptor (BCR) signal transduction and activation, and preventing tumor cell activation, migration, adhesion, and proliferation. It has potential immunomodulatory and anti-tumor activity.
CAS:
1415792-84-5
Formula:
0
Molecular Weight:
0
Pathway:
Tyrosine Kinase/Adaptors|Angiogenesis
Purity:
0.98
SMILES:
Unknown
Target:
Syk

References

Su WG, et al. Preparation of pyridopyrazine derivatives for use as Syk inhibitors. WO2012167733 A1. Na Yang, et al. HMPL-523, a Novel SYK Inhibitor Showed Anti-Tumor Activities In Vitro and In Vivo. Blood (2016) 128 (22): 3970.