ThioGlo1

TargetMol
Product Code: TAR-T38076
Supplier: TargetMol
CodeSizePrice
TAR-T38076-10mg10mg£141.00
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TAR-T38076-50mg50mg£328.00
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Quantity:
TAR-T38076-100mg100mg£512.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
ThioGlo1 is a thiol-reactive fluorescent probe.1,2,3Upon reaction with a thiol group, a fluorescent adduct is formed that displays excitation/emission maxima of 384/513 nm, respectively.2,3It also reacts with sulfite to form a fluorescent adduct with similar spectral characteristics, and interference from sulfite during thiol determination must be accounted for using secondary methods. ThioGlo1 has been used to monitor the oxidative stability of beer.
CAS:
137350-66-4
Formula:
C20H13NO7
Molecular Weight:
379.324
Purity:
0.98
SMILES:
COC(=O)c1cc2c(ccc3ccc(OC)c(N4C(=O)C=CC4=O)c23)oc1=O

References

Hoff, S., Larsen, F.S., Anderson, M.L., et al.Quantification of protein thiols using ThioGlo 1 fluorescent derivatives and HPLC separationAnalyst138(7)2096-2103(2013) Yang, J.-R., and Langmuir, M.E.Synthesis and properties of a maleimide fluorescent thiol reagent derived from a naphthopyranoneJ. Heterocycl. Chem.28(5)1177-1180(1991) Lund, M.N., and Andersen, M.L.Detection of thiol groups in beer and their correlation with oxidative stabilityJ. Am. Soc. Brew. Chem.69(3)163-169(2011)