Phosphatidylethanolamines (soy)

TargetMol
Product Code: TAR-T38142
Supplier: TargetMol
CodeSizePrice
TAR-T38142-10mg10mg£602.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T38142-25mg25mg£1,013.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T38142-50mg50mg£1,560.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Further Information

Bioactivity:
Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E. coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. Phosphatidylethanolamines (soy) is a mixture of phosphatidylethanolamines isolated from soy with various fatty acyl groups at the sn-1 and sn-2 positions.
CAS:
97281-51-1
Formula:
N/A
Molecular Weight:
0
Purity:
0.98
SMILES:
[R]C(OC[C@@H](OC([R])=O)COP([O-])(OCC[NH3+])=O)=O

References

Deleault, N.R., Piro, J.R., Walsh, D.J., et al. Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids Proc. Natl. Acad. Sci. U.S.A. 109(22), 8546-8551 (2012). Vance, J.E., and Tasseva, G. Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells Biochim. Biophys. Acta 1831(3), 543-554 (2013). Bogdanov, M., Sun, J., Kaback, H.R., et al. A phospholipid acts as a chaperone in assembly of a membrane transport protein J. Biol. Chem. 271(20), 11615-11618 (1996).