SN52

TargetMol
Product Code: TAR-T38460
Supplier: TargetMol
CodeSizePrice
TAR-T38460-10mg10mg£704.00
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Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
SN52 is a potent, competitive, and cell-permeable inhibitor of NF-κB2 . SN52 is a variant of the SN50 peptide and inhibits the nuclear translocation of p52-RelB heterodimers. SN52 has a strong radiosensitization effect on prostate cancer cells. SN52 can be used for cancer research.
CAS:
1071173-56-2
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Yuzhu Hou, et al. Non-canonical NF-?B Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Immunity. 2018 Sep 18;49(3):490-503.e4 Yong Xu, et al. SN52, a novel nuclear factor-kappaB inhibitor, blocks nuclear import of RelB:p52 dimer and sensitizes prostate cancer cells to ionizing radiation. Mol Cancer Ther