Fomivirsen sodium

TargetMol
Product Code: TAR-T39068
Supplier: TargetMol
CodeSizePrice
TAR-T39068-10mg10mg£870.00
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Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Fomivirsen sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is an antiviral agent that is used cytomegalovirus retinitis (CMV) research, incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein (required for viral replication), thus providing bioactive effects for CMV retinitis by inhibition of virus proliferation.
CAS:
160369-77-7
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

M D de Smet, et al. Fomivirsen- a phosphorothioate oligonucleotide for the treatment of CMV retinitis. Ocul Immunol Inflamm. 1999 Dec;7(3-4):189-98. Anna Kilanowska, et al. In vivo and in vitro studies of antisense oligonucleotides ? a review. (Review Article)?RSC Adv., 2020,?10, 34501-34516