ALV2
Code | Size | Price |
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TAR-T40099-10mg | 10mg | £604.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T40099-25mg | 25mg | £1,163.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
ALV2 is a potent and selective Helios degrader. ALV2 binds CRBN, with an IC 50 of 0.57 μM. Helios is the zinc-finger transcription factor that can maintain a stable T reg cell phenotype in the inflammatory tumor microenvironment.
CAS:
2438124-95-7
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Wang ES, et, al. Acute pharmacological degradation of Helios destabilizes regulatory T cells. Nat Chem Biol. 2021 Jun;17(6):711-717.