4-Octyl itaconate
| Code | Size | Price |
|---|
| TAR-T4580-50mg | 50mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T4580-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
4-Octyl Itaconate is a cell-permeable Itaconate derivative and an anti-inflammatory metabolite. Itaconate activates Nrf2 via alkylation of KEAP1.
CAS:
3133-16-2
Formula:
C13H22O4
Molecular Weight:
242.315
Pathway:
Immunology/Inflammation
Purity:
0.9982
SMILES:
CCCCCCCCOC(=O)CC(=C)C(O)=O
Target:
Nrf2
References
Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.
Wang S J, Ye W, Li W Y, et al.Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.Journal of Ethnopharmacology.2022: 116053.