TargetMol

Astragaloside

Product Code:
 
TAR-T4S0823
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4S0823-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T4S0823-50mg50mg£207.00
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Further Information

Bioactivity:
Astragaloside may protect against brain contusion and neuronal apoptosis after TBI by attenuating microglia activation in male rats. Astragalosides-induced apoptosis in NB4 cells may be associated with down-regulation of the expression of BCL-2 and NF-κB, finally the relative activity of caspase-3 activated. Astragaloside has several pharmacological actions on cardiovascular system, including positive inotropic, anti-arrhythmia and anti-oxidant activities; it also has anti-apoptotic activity, which may contribute to the improvement of clinical outcomes in treating myocarditis with pharmaceutics of Astragalus membranaceus.
CAS:
17429-69-5
Formula:
C28H32O17
Molecular Weight:
640.547
Purity:
0.98
SMILES:
COc1cc(ccc1O)-c1oc2cc(O)cc(O)c2c(=O)c1O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O

References

Yin Y Y , Li W P , Gong H L , et al. Protective Effect of Astragaloside on Focal Cerebral Ischemia/Reperfusion Injury in Rats[J]. American Journal of Chinese Medicine, 2010, 38(03):517-527.