TargetMol

pyridoxal isonicotinoyl hydrazone

Product Code:
 
TAR-T5314
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5314-10mg10mg£107.00
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TAR-T5314-50mg50mg£141.00
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TAR-T5314-100mg100mg£179.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pyridoxal isonicotinoyl hydrazine is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo.
CAS:
737-86-0
Formula:
C14H14N4O3
Molecular Weight:
286.291
Purity:
0.9991
SMILES:
Cc1ncc(CO)c(C=NNC(=O)c2ccncc2)c1O

References

Brewer CT, et al. The Isoniazid Metabolites Hydrazine and Pyridoxal Isonicotinoyl Hydrazone Modulate Heme Biosynthesis. Toxicol Sci. 2019 Mar 1;168(1):209-224. 1. Richardson DR, et al. Pyridoxal isonicotinoyl hydrazone and its analogs: potential orally effective iron-chelating agents for the treatment of iron overload disease. J Lab Clin Med. 1998 Apr;131(4):306-15.