TargetMol

(±)-Norcantharidin

Product Code:
 
TAR-T5656
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5656-10mg10mg£111.00
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TAR-T5656-25mg25mg£128.00
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TAR-T5656-50mg50mg£156.00
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This product comes from: United States.
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Further Information

Bioactivity:
Endothall Anhydride is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers.
CAS:
29745-04-8
Formula:
C8H8O4
Molecular Weight:
168.148
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; JAK/STAT signaling
Purity:
0.98
SMILES:
O=C1OC(=O)[C@@H]2[C@H]3CC[C@H](O3)[C@H]12
Target:
EGFR; c-Met/HGFR

References

Fan Y Z , Zhao Z M , Fu J Y , et al. Norcantharidin Inhibits Growth of Human Gallbladder Carcinoma Xenografted Tumors in Nude Mice by Inducing Apoptosis and Blocking the Cell Cycle in vivo[J]. Hepatobiliary & Pancreatic Diseases International, 2010, 9(4):414-422. Qiu P , Wang S , Liu M , et al. Norcantharidin Inhibits cell growth by suppressing the expression and phosphorylation of both EGFR and c-Met in human colon cancer cells[J]. BMC Cancer, 2017, 17(1):55.