7-Nitroindazole

TargetMol
Product Code: TAR-T7474
Supplier: TargetMol
CodeSizePrice
TAR-T7474-500mg500mg£103.00
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Quantity:
TAR-T7474-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.
CAS:
2942-42-9
Formula:
C7H5N3O2
Molecular Weight:
163.136
Pathway:
Immunology/Inflammation
Purity:
0.9615
SMILES:
[O-][N+](=O)c1cccc2cn[nH]c12
Target:
NOS

References

Vessela V , Rumyana S , Magdalena K B , et al. Selective Nitric Oxide Synthase Inhibitor 7-Nitroindazole Protects against Cocaine-Induced Oxidative Stress in Rat Brain[J]. Oxidative Medicine and Cellular Longevity, 2015, 2015:1-8. Zagvazdin Y , Sancesario G , Wang Y X , et al. Evidence from its cardiovascular effects that 7-nitroindazole may inhibit endothelial nitric oxide synthase in vivo.[J]. European Journal of Pharmacology, 1996, 303(1?2):61-69. Fang W, Wang X, Cai M, et al. Targeting GluN2B/NO Pathway Ameliorates Social Isolation?Induced Exacerbated Attack Behavior in Mice. Frontiers in Pharmacology. 2021: 1667.