Methotrexate disodium
Code | Size | Price |
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TAR-T8003-50mg | 50mg | £98.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8003-100mg | 100mg | £109.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8003-200mg | 200mg | £121.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T8003-500mg | 500mg | £173.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
CAS:
7413-34-5
Formula:
C20H20N8Na2O5
Molecular Weight:
498.4
Pathway:
Cell Cycle/Checkpoint; Apoptosis; DNA Damage/DNA Repair; Metabolism
Purity:
0.9977
SMILES:
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)[O-])C(=O)[O-])cc1.[Na+].[Na+]
Target:
Apoptosis; Dehydrogenase; DNA/RNA Synthesis; Antifolate
References
Yang W , Zou Y , Meng F , et al. Efficient and Targeted Suppression of Human Lung Tumor Xenografts in Mice with Methotrexate Sodium Encapsulated in All-Function-in-One Chimeric Polymersomes[J]. Advanced Materials, 2016, 28(37):8234-8239.
Yang W , Xia Y , Fang Y , et al. Selective Cell Penetrating Peptide-Functionalized Polymersomes Mediate Efficient and Targeted Delivery of Methotrexate Disodium to Human Lung Cancer In Vivo[J]. Advanced Healthcare Materials, 2017:1701135.