TargetMol

Cetirizine Impurity B dihydrochloride

Product Code:
 
TAR-T9084
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9084-10mg10mg£108.00
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TAR-T9084-1mL1 mL * 10 mM (in DMSO)£115.00
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TAR-T9084-25mg25mg£138.00
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TAR-T9084-50mg50mg£176.00
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TAR-T9084-100mg100mg£228.00
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TAR-T9084-200mg200mg£306.00
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Further Information

Bioactivity:
Cetirizine Impurity B dihydrochloride is an impurity of Cetirizine dihydrochloride. Cetirizine is a second-generation antihistamine. Cetirizine is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
CAS:
1000690-91-4
Formula:
C19H23Cl3N2O2
Molecular Weight:
417.76
Pathway:
Neuroscience; GPCR/G Protein; Immunology/Inflammation
Purity:
0.9924
SMILES:
Cl.Cl.OC(=O)CN1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1
Target:
Histamine Receptor

References

Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.