P-3FAX-Neu5Ac
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
P-3FAX-Neu5Ac is a sialic acid analog and a sialyltransferase inhibitor.
CAS:
117405-58-0
Formula:
C22H30FNO14
Molecular Weight:
551.47
Pathway:
Metabolism
Purity:
0.98
SMILES:
COC(=O)C1(OC(C)=O)OC([C@H](OC(C)=O)[C@@H](COC(C)=O)OC(C)=O)C(NC(C)=O)C(OC(C)=O)C1F
Target:
Transferase
References
Rillahan CD, et al. Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome. Nat Chem Biol. 2012 Jul;8(7):661-8.
Gupta R, et al. Serine hydroxymethyl transferase 1 stimulates pro-oncogenic cytokine expression through sialic acid to promote ovarian cancer tumor growth and progression. Oncogene. 2017 Jul 13;36(28):4014-4024.