TargetMol

Trachelogenin

Product Code:
 
TAR-TN6508
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN6508-1mg1mg£213.00
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TAR-TN6508-5mg5mg£424.00
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TAR-TN6508-1mL1 mL * 10 mM (in DMSO)£440.00
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TAR-TN6508-10mg10mg£591.00
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TAR-TN6508-25mg25mg£863.00
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TAR-TN6508-50mg50mg£1,187.00
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This product comes from: United States.
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Further Information

Bioactivity:
Trachelogenin has antiproliferative effect, the mechanism is related to affect the phosphorylation of key proteins such as β-Catenin, c-Myc and GSK3 in the β-Catenin signaling pathway in a concentration-dependent manner.
CAS:
34209-69-3
Formula:
C21H24O7
Molecular Weight:
0
Pathway:
Cell Cycle/Checkpoint|Microbiology/Virology|Proteases/Proteasome|Cytoskeletal Signaling|Stem Cells
Purity:
0.98
SMILES:
0
Target:
Virus Protease|Wnt/beta-catenin|c-Myc|HCV Protease

References

Mervai Z, et al. Endogenous enzyme-hydrolyzed fruit of Cirsium brachycephalum: optimal source of the antiproliferative lignan trachelogenin regulating the Wnt/?-catenin signaling pathway in the SW480 colon adenocarcinoma cell line. Fitoterapia. 2015;100:19-26. Koech PK, et al. Anti-glutamatergic Effects of Three Lignan Compounds: Arctigenin, Matairesinol and Trachelogenin - An ex vivo Study on Rat Brain Slices. Planta Med. 2023;89(9):879-889. Qian XJ, et al. Trachelogenin, a novel inhibitor of hepatitis C virus entry through CD8J Gen Virol. 2016;97(5):1134-1144.