TargetMol

Warangalone

Product Code:
 
TAR-TQ0072
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0072-5mg5mg£568.00
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Further Information

Bioactivity:
Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively.
CAS:
4449-55-2
Formula:
C25H24O5
Molecular Weight:
404.462
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
CC(C)=CCc1c2OC(C)(C)C=Cc2c(O)c2c1occ(-c1ccc(O)cc1)c2=O
Target:
PKA

References

Tati Herlina, et al. ANTI-MALARIAL COMPOUND FROM THE STEM BARK OF Erythrina variegate. Indo. J. Chem., 2009, 9 (2), 308-311. Wang BH, et al. Specific inhibition of cyclic AMP-dependent protein kinase by warangalone and robustic acid. Phytochemistry. 1997 Mar;44(5):787-96. Induction of apoptosis by isoflavonoids from the leaves of Millettia taiwaniana in human leukemia HL-60 cells. Planta Med. 2006 Apr;72(5):424-9.