Progesterone
| Code | Size | Price |
|---|
| TAR-T0478-50mg | 50mg | £101.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T0478-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T0478-100mg | 100mg | £114.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Progesterone is the major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production.
CAS:
57-83-0
Formula:
C21H30O2
Molecular Weight:
314.469
Pathway:
Neuroscience; Metabolism; ; GPCR/G Protein; Endocrinology/Hormones
Purity:
0.9989
SMILES:
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Target:
Estrogen/progestogen Receptor; Progesterone Receptor; Opioid Receptor; Endogenous Metabolite
References
1. Owen GI, et al. J Biol Chem,1998, 273(17), 10696-10701.
2. Joshi PA, et al. Nature,2010, 465(7299), 803-807.
3. Bitran D, et al. Pharmacol Biochem Behav,1993, 45(2), 423-428.
4. Carroll JC, et al. J Neurosci,2007, 27(48), 13357-13365.
5. Roof RL, et al. Exp Neurol,1994, 129(1), 64-69.
6. Wang D, Jin M, Zhou Y, et al. Loss of miR-29a Impairs Decidualisation of Endometrial Stromal Cells by Enhancing TET3 Binding to the Col1A1 Promoter[J]. Available at SSRN 3797277.
7. Zhang S, Sun C, Zhao S, et al. Exposure to DEHP or its metabolite MEHP promotes progesterone secretion and inhibits proliferation in mouse placenta or JEG-3 cells[J]. Environmental Pollution. 2020, 257: 113593.
8. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks[J]. Chemical Science. 2020, 11(7): 1775-1797.