TargetMol

Cortisone acetate

Product Code:
 
TAR-T0034
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0034-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T0034-100mg100mg£118.00
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TAR-T0034-500mg500mg£148.00
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Further Information

Bioactivity:
Cortisone Acetate is the acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.
CAS:
50-04-4
Formula:
C23H30O6
Molecular Weight:
402.49
Pathway:
Metabolism; Endocrinology/Hormones
Purity:
0.9973
SMILES:
CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C
Target:
Glucocorticoid Receptor; Endogenous Metabolite

References

1. Grossman R, et al. Ann N Y Acad Sci. 2006, 1071:410-21.