Naloxone hydrochloride

TargetMol
Product Code: TAR-T0102
Supplier: TargetMol
CodeSizePrice
TAR-T0102-100mg100mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T0102-200mg200mg£120.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
Naloxone hydrochloride is a specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.
CAS:
357-08-4
Formula:
C19H22ClNO4
Molecular Weight:
363.84
Pathway:
Neuroscience; Endocrinology/Hormones; GPCR/G Protein
Purity:
0.998
SMILES:
Cl.Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
Target:
Opioid Receptor

References

1. Liu B, et al. J Pharmacol Exp Ther, 2000, 293(2), 607-617. 2. Froehlich JC, et al. Pharmacol Biochem Behav, 1990, 35(2), 385-390. 3. Gallate JE, et al. Psychopharmacology (Berl), 1999, 142(3), 302-308. 4. Liu B, et al. J Pharmacol Exp Ther, 2000, 295(1), 125-132. 5. Li Y, Shi X, Cai X, et al. microRNA-422a Inhibits DCC Expression in a Manner Dependent on SNP rs12607853[J]. Cytogenetic and Genome Research. 2020, 160(2): 63-71. 6. Guo H, Xie Q, Cui J, et al. Naloxone reversed cognitive impairments induced by repeated morphine under heavy perceptual load in the 5?choice serial reaction time task[J]. Journal of neuroscience research. 2019 May 12.