TargetMol

Irinotecan hydrochloride trihydrate

Product Code:
 
TAR-T0486
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0486-25mg25mg£101.00
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TAR-T0486-50mg50mg£114.00
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TAR-T0486-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T0486-100mg100mg£128.00
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This product comes from: United States.
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Further Information

Bioactivity:
Irinotecan HCl-trihydrate keeps DNA from unwinding by inhibiting topoisomerase 1.
CAS:
136572-09-3
Formula:
C33H45ClN4O9
Molecular Weight:
677.19
Pathway:
DNA Damage/DNA Repair; Autophagy
Purity:
0.9979
SMILES:
O.O.O.Cl.CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OC(=O)N3CCC(CC3)N3CCCCC3)cc12
Target:
Topoisomerase; Autophagy

References

1. Pavillard V, et al. Cancer Chemother Pharmacol. 2002, 49(4), 329-335. 2. Tobin P, et al. Br J Clin Pharmacol. 2006, 62(1), 122-129. 3. Shingyoji M, et al. Cancer Sci. 2004, 95(6), 537-540. 4. van Ark-Otte J, et al. Br J Cancer. 1998, 77(12), 2171-2176. 5. Jansen WJ, et al. Int J Cancer. 1997, 70(3):335-340.