Hydroxychloroquine sulfate
| Code | Size | Price |
|---|
| TAR-T0951-50mg | 50mg | £109.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T0951-100mg | 100mg | £130.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Hydroxychloroquine sulfate inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa.
CAS:
747-36-4
Formula:
C18H28ClN3O5S
Molecular Weight:
433.95
Pathway:
Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology
Purity:
0.9987
SMILES:
OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
Target:
DNA; SARS-CoV; TLR; Parasite; Autophagy
References
1. Ramser B, et al.J Invest Dermatol, 2009,129(10):2419-26.
2. Lee HO, et al. PLoS One. 2015, 10(7): e20131464.
3. Bourke L, et al. PLoS One. 2015, 10(12):e0143771.
4. Marta Mosca, et al. 2013 ACR/ARHP Annual Meeting.
5. Lamphier M, et al. Mol Pharmacol. 2014, 85(3):429-440.
6. Manzo C, et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4(1):6.
7. Xia Z, Zhang X, Liu P, et al. GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner[J]. Cell Death & Disease. 2021, 12(1): 1-11.