Cephalothin sodium
| Code | Size | Price |
|---|
| TAR-T1122-100mg | 100mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin Sodium is the sodium salt form of cephalothin, a semisynthetic, beta-lactam, the first-generation cephalosporin antibiotic with bactericidal activity. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
CAS:
58-71-9
Formula:
C16H15N2NaO6S2
Molecular Weight:
418.41
Pathway:
Microbiology/Virology
Purity:
0.9917
SMILES:
[Na+].CC(=O)OCC1=C(N2C(SC1)C(NC(=O)Cc1cccs1)C2=O)C([O-])=O
Target:
Antibacterial; Antibiotic
References
1. Williamson R, et al. Antimicrob Agents ChemOthers. 1980 Oct;18(4):629-37.