GSK-843
Code | Size | Price |
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TAR-T11474-5mg | 5mg | £254.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T11474-50mg | 50mg | £1,066.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T11474-100mg | 100mg | £1,669.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
GSK-843 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor ( IC50: 8.6 nM for binding RIP3 kinase domain; IC50: 6.5 nM for inhibiting kinase activity).
CAS:
1601496-05-2
Formula:
C19H15N5S2
Molecular Weight:
377.48
Pathway:
Apoptosis
Purity:
0.98
SMILES:
Cc1cc(-c2cnc(N)c3c(csc23)-c2ccc3scnc3c2)n(C)n1
Target:
TNF
References
1. Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.