(-)-Bicuculline methobromide
Code | Size | Price |
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TAR-T12043-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
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TAR-T12043-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Documents
Further Information
Bioactivity:
(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .
CAS:
73604-30-5
Formula:
C21H20BrNO6
Molecular Weight:
462.296
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.98
SMILES:
[Br-].C[N+]1(C)CCc2cc3OCOc3cc2[C@@H]1[C@H]1OC(=O)c2c1ccc1OCOc21
Target:
GABA Receptor
References
1. Seutin V, et al. Recent advances in the pharmacology of quaternary salts of bicuculline. Trends Pharmacol Sci. 1999 Jul;20(7):268-70.
2. Okazaki R, et al. The antiallodynic effect of Neurotropin is mediated via activation of descending pain inhibitory systems in rats with spinal nerve ligation. Anesth Analg. 2008 Sep;107(3):1064-9.