PF-03654746 Tosylate
Code | Size | Price |
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TAR-T12416-5mg | 5mg | £309.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T12416-50mg | 50mg | £1,018.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T12416-100mg | 100mg | £1,508.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
PF-03654746 Tosylate is selective antagonist of histamine H3 receptor with high brain penetration.
CAS:
1039399-17-1
Formula:
C25H32F2N2O4S
Molecular Weight:
494.6
Pathway:
Immunology/Inflammation; GPCR/G Protein; Neuroscience
Purity:
0.98
SMILES:
Cc1ccc(cc1)S(O)(=O)=O.CCNC(=O)[C@H]1C[C@@](F)(C1)c1ccc(CN2CCCC2)c(F)c1
Target:
Histamine Receptor
References
1. Stokes JR, et al. The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms. J Allergy Clin Immunol. 2012 Feb;129(2):409-12, 412.e1-2.
2. Brioni JD, et al. Discovery of histamine H3 antagonists for the treatment of cognitive disorders and Alzheimer's disease. J Pharmacol Exp Ther. 2011 Jan;336(1):38-46.