Methotrexate
Code | Size | Price |
---|
TAR-T1485-50mg | 50mg | £101.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1485-1mL | 1 mL * 10 mM (in DMSO) | £114.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1485-100mg | 100mg | £114.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1485-200mg | 200mg | £136.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1485-500mg | 500mg | £185.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Methotrexate is a folate analog metabolic inhibitor with immunosuppressant and antineoplastic properties.
CAS:
59-05-2
Formula:
C20H22N8O5
Molecular Weight:
454.447
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Apoptosis
Purity:
0.9946
SMILES:
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Target:
Apoptosis; Dehydrogenase; DNA/RNA Synthesis; Antifolate
References
1. Genestier L, et al. J Clin Invest, 1998, 102(2), 322-328.
2. Chan ES, et al. Arthritis Res, 2002, 4(4), 266-273.
3. Cronstein BN, et al. J Clin Invest, 1993, 92(6), 2675-2682.
4. Bennett BC, et al. J Med Chem. 2007, 50(18):4374-81.