Daun02
| Code | Size | Price |
|---|
| TAR-T15054-25mg | 25mg | £670.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.
CAS:
290304-24-4
Formula:
C41H44N2O20
Molecular Weight:
884.797
Pathway:
DNA Damage/DNA Repair
Purity:
0.98
SMILES:
COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](NC(=O)OCc6ccc(O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O)c(c6)[N+]([O-])=O)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O
Target:
Topoisomerase
References
1. Koya E, et al. Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization. Nat Neurosci. 2009 Aug;12(8):1069-73.
2. Lehmann M, et al. Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test. Environ Mol Mutagen. 2004;43(4):250-7.
3. Farquhar D, et al. Suicide gene therapy using E. coli beta-galactosidase.Cancer Chemother Pharmacol. Cancer Chemother Pharmacol. 2002 Jul;50(1):65-70.