Ro15-4513
Code | Size | Price |
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TAR-T16775-5mg | 5mg | £291.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T16775-50mg | 50mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T16775-100mg | 100mg | £1,492.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist.
CAS:
91917-65-6
Formula:
C15H14N6O3
Molecular Weight:
326.316
Purity:
0.98
SMILES:
CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(ccc-21)N=[N+]=[N-]
References
1. Bonetti EP, et al. Ro 15-4513: partial inverse agonism at the BZR and interaction with ethanol. Pharmacol Biochem Behav. 1988 Nov;31(3):733-49.
2. Suzdak PD, et al. Effects of Ro15-4513 and other benzodiazepine receptor inverse agonists on alcohol-inducedintoxication in the rat. J Pharmacol Exp Ther. 1988 Jun;245(3):880-6.
3. Linden AM, et al. Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through ???2-type GABA(A) Receptors. Front Neurosci. 2011 Jan 20;5:3.