Diosmetin
Code | Size | Price |
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TAR-T1704-25mg | 25mg | £98.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1704-50mg | 50mg | £109.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1704-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1704-100mg | 100mg | £123.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Diosmetin has been found to act as a weak TrkB receptor agonist.
CAS:
520-34-3
Formula:
C16H12O6
Molecular Weight:
300.266
Pathway:
Tyrosine Kinase/Adaptors; Metabolism
Purity:
0.98
SMILES:
COc1ccc(cc1O)-c1cc(=O)c2c(O)cc(O)cc2o1
Target:
P45; Trk receptor
References
1. Sher E, et al. Pharmacol Res, 1992, 26(4), 395-402.
2. Morel I, et al. Biochem Pharmacol, 1993, 45(1), 13-19.
3. Ciolino HP, et al. Cancer Res, 1998, 58(13), 2754-2760.
4. Quintieri L, et al. Drug Metab Pharmacokinet, 2011, 26(6), 559-568.
5. Yu G, et al. Diosmetin ameliorates the severity of cerulein-induced acute pancreatitis in mice by inhibiting the activation of the nuclear factor-?B. Int J Clin Exp Pathol. 2014 Apr 15;7(5):2133-42.
6. Liu B, et al. Diosmetin induces apoptosis by upregulating p53 via the TGF-? signal pathway in HepG2 hepatoma cells. Mol Med Rep. 2016 Jul;14(1):159-64.